Acute Myocardial Infarction: Evaluation with First-Pass Enhancement and Delayed Enhancement MR Imaging Compared with201Tl SPECT Imaging

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Abstract
PURPOSE: To evaluate acute myocardial infarction by using first-pass enhancement (FPE) and delayed enhancement (DE) magnetic resonance (MR) imaging compared with thallium 201 (201Tl) single photon emission computed tomography (SPECT). MATERIALS AND METHODS: Contrast material–enhanced FPE MR, inversion-recovery DE MR, and rest-redistribution 201Tl SPECT images were obtained in 60 consecutive patients (53 men, seven women; mean age [± SD], 56 years ± 13; range, 30–78 years) at 6 days ± 3 after reperfused first myocardial infarction. Presence of microvascular obstruction was determined on FPE MR images. Infarct size was defined on DE MR images as percentage of left ventricular (LV) area and compared with uptake defect on redistribution 201Tl SPECT images. Differences in continuous data were analyzed with Student t test. Linear regression and Bland-Altman analysis were used to compare measurements of infarct size. RESULTS: Mean infarct size was not significantly different between DE MR imaging (20.7% ± 11.5% ...