FLUCTUATION IN THE HYDROGEN ION CONCENTRATION OF SALIVA IN EPILEPSY

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Abstract
Epilepsy had for a long time been considered a condition of acidosis of the system. The nonmedicinal treatment consisted of restricting meats and of replacing them with vegetables to reduce the acidity. Bisgaard and Norvig were the first to demonstrate that rather the opposite, an alkalosis, was the underlying condition in epilepsy. They demonstrated the retention of basic substances in the blood serum and urine. This dysregulation, as it was called, was attributed to a disturbed function of the parathyroid gland. I had an opportunity to visit St. Hans Hospital in Denmark at the time this work was being done. Norvig at that time was treating his patients with parathyroid gland, which was extracted with physiologic sodium chloride solution and was injected into the patient immediately. He explained that the commercial parathyroid extracts were unsatisfactory on account of the marked instability of the active principle. He succeeded in cutting down

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