Synthesis and Biological Evaluation of a Cyclo--tetrapeptide as a Somatostatin Analogue
- 3 May 1999
- journal article
- research article
- Published by Wiley in Angewandte Chemie International Edition in English
- Vol. 38 (9) , 1223-1226
- https://doi.org/10.1002/(sici)1521-3773(19990503)38:9<1223::aid-anie1223>3.0.co;2-a
Abstract
Short β -peptides can mimic natural peptide hormones, as has been shown with a cyclo-β-tetrapeptide (1) that displays micromolar affinity to human somatostatin receptors. β-Peptides are thus a promising new class of peptidomimetics with potential high bioavailability due to their excellent resistance against proteases.This publication has 0 references indexed in Scilit: