Pharmacokinetic Studies of the Fragrance Compound 1,8-Cineol in Humans during Inhalation
Open Access
- 1 January 1996
- journal article
- Published by Oxford University Press (OUP) in Chemical Senses
- Vol. 21 (4) , 477-480
- https://doi.org/10.1093/chemse/21.4.477
Abstract
The present study was undertaken to investigate the pharmacokinetics of 1,8-cineol in human subjects during prolonged inhalation. The results showed that 1,8-cineol is well absorbed from breathing air, with a peak plasma concentration after ∼18 min. The elimination of this fragrance compound from the blood is biphasic, with a mean distribution half-life of 6.7 min and an elimination half-life of 104.6 min. Chem. Senses 21: 477–480, 1996.Keywords
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