An Epidemic of Acute Hemorrhagic Conjunctivitis in Sendai Area, 1973-1974

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Abstract
In 1973 and 1974, an epidemic of acute hemorrhagic conjunctivitis (AHC) with a tendency of less frequent conjunctival hemorrhage occurred among the staff of the National Railways and their families in the Sendai area [Japan]. Four strains of AHC virus and 4 strains (1 of type 7 and 3 of type 8) of adenoviruses were isolated from 22 conjunctival swabs of the patients. Of 55 cases examined, 36 (66%) were proved serologically to be an AHC virus infection, and 7 cases (13%) were adenovirus infection. Clinically infrequent association of hemorrhagic conjunctivitis was remarkable. Only 10 cases (28%) had detectable signs of hemorrhagic conjunctivitis. There were no substantial changes in antigenicity and optimum temperature for virus multiplication between prototype and isolated strains. The isolated strains seemed to be less neutralizable and less producible at 29.degree. C than the prototype strain.

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