The Effect of Calcium and Phosphorus on the Metabolism of Lead

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Abstract
The effect of varying the concentration of calcium and phosphorus in diets containing low concentrations of lead (16 to 32 p.p.m.) on the retention of lead was investigated in a series of five experiments involving 128 growing or adult rats. In some of these experiments the retention of calcium and phosphorus was also measured. All mineral retentions were measured by carcass analysis. An essential feature of the experiments was the equalization of the food intakes of rats on comparable diets, thus permitting the interpretation of the results in terms solely of the relative compositions of the diets. The results obtained appear to warrant the following conclusions: