CHROMOSOME 21 PARTIAL TRISOMIES DUE TO A MATERNAL TRANSLOCATION T(15-21) (Q262-Q21)
- 1 January 1976
- journal article
- research article
- Vol. 19 (3) , 187-190
Abstract
A balanced reciprocal translocation, t(15;21) (q262;q21), was observed in the mother and maternal grandfather of 2 patients. The propositus, who received the abnormal chromosome 15 from his mother, is trisomic for the distal part of chromosome 21, and his phenotype is that of classical trisomy 21. His sister, who is trisomic for the proximal part of 21q, is slightly retarded but developmentally normal.This publication has 1 reference indexed in Scilit:
- Down’s Syndrome Associated with a Familial (21q—;22q+) TranslocationCytogenetic and Genome Research, 1967