Evaluation of Four Whole-Cell Leptospira -Based Serological Tests for Diagnosis of Urban Leptospirosis
- 1 September 2007
- journal article
- Published by American Society for Microbiology in Clinical and Vaccine Immunology
- Vol. 14 (9) , 1245-1248
- https://doi.org/10.1128/cvi.00217-07
Abstract
Four serologic assays for leptospirosis had sensitivities of 72 to 88% and specificities of 88 to 100% in the setting of highly endemic urban transmission, indicating that assays using enzyme-linked immunosorbency and rapid formats may be used as alternatives to the microscopic agglutination test for diagnosing urban leptospirosis. Testing a second sample will be required in cases with an initial negative result, since sensitivity was low (46 to 68%) during the first week of illness.Keywords
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