ASYMMETRIC REDUCTION OF PROCHIRAL KETO ESTERS WITH A CHIRAL REDUCING AGENT PREPARED FROM TIN(II) CHLORIDE, CHIRAL DIAMINE, AND DIISOBUTYLALUMINUM HYDRIDE
- 5 June 1985
- journal article
- research article
- Published by Oxford University Press (OUP) in Chemistry Letters
- Vol. 14 (6) , 813-816
- https://doi.org/10.1246/cl.1985.813
Abstract
Asymmetric reduction of prochiral keto esters with a reagent, generated by treatment of a mixture of tin(II) chloride and a chiral diamine derived from (S)-proline with diisobutylaluminum hydride, afforded the corresponding optically active hydroxy esters.Keywords
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