Sensitization to Calciphylaxis by Endogenous Parathyroid Hormone
- 1 October 1962
- journal article
- research article
- Published by The Endocrine Society in Endocrinology
- Vol. 71 (4) , 554-558
- https://doi.org/10.1210/endo-71-4-554
Abstract
Earlier work has shown that pretreatment with parathyroid extract sensitizes the rat to the production of a calciphylactic syndrome characterized by selective calcinosis in the left auricular appendage and the extrahepatic bile-duct system. The present experiments indicate that similar sensitization can be achieved by bilateral nephrectomy, but only in the presence of the parathyroids. Hence, it may be concluded that autologous parathyroid hormone in amounts secreted by the glands can act as a calciphylactic sensitizer.Keywords
This publication has 2 references indexed in Scilit:
- PREVENTION OF CALCIPHYLAX1S BY HYPOPHYSECTOMY1Endocrinology, 1961
- CAUSATIVE RELATIONSHIPS OF PARATHYROID HORMONE TO RENOGENIC AND RENIPRIVAL CARDIOVACULAR DISEASEAnnals of the New York Academy of Sciences, 1959