Automated static perimetry and nerve fibre layer defects in glaucoma and controls

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Abstract
Correlation of psychophysical tests and structural changes is essential in the management of glaucoma. We compared the mean sensitivity and the short-term fluctuation in eyes with and without defects in the retinal nerve fibre layer in 41 glaucoma patients and 40 controls. In the glaucoma group 87.2% of eyes with visual field defects and 42.3% without visual field defects showed nerve fibre loss. In the control group 36.3% showed nerve fibre loss. In manifest glaucoma the mean sensitivity was 10.9 +/- 7.2 dB in eyes with nerve fibre loss and 19.2 +/- 3.9 dB in eyes without nerve fibre loss. This difference was statistically significant. The corresponding difference in glaucoma suspects and controls was not statistically significant. There was no difference between the short-term fluctuation in the three groups regardless of nerve fibre loss.