Phantom experiment and calculation for in vivo10boron analysis by prompt gamma ray spectroscopy
- 1 March 1991
- journal article
- Published by IOP Publishing in Physics in Medicine & Biology
- Vol. 36 (3) , 329-338
- https://doi.org/10.1088/0031-9155/36/3/002
Abstract
In order to determine 10B concentrations in a tumour in vivo without injuring tissues, phantom experiments and calculations were carried out for boron neutron capture therapy. The experiment was based on prompt gamma ray spectroscopy and a single-crystal silicon-filtered neutron beam from a TRIGA-II reactor. Calibration curves to determine the 10B concentrations in the tumours were experimentally generated from known 10B values for simulated tumours with various volumes in a phantom. The 10B distributions in a tumour were also investigated and it was possible to distinguish the tumour with 10B from normal tissue without 10B. In addition, the 10B concentrations were estimated by calculations.Keywords
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