THE PRECIPITIN REACTION BETWEEN DNA AND A SERUM FACTOR IN SYSTEMIC LUPUS ERYTHEMATOSUS
Open Access
- 1 January 1959
- journal article
- research article
- Published by Rockefeller University Press in The Journal of Experimental Medicine
- Vol. 109 (1) , 97-114
- https://doi.org/10.1084/jem.109.1.97
Abstract
The sera of certain patients with systemic lupus erythematosus contain an antibody-like substance capable of reacting with highly purified DNA preparations from widely divergent sources. Precipitin reactions have been demonstrated by double diffusion in agar and quantitative precipitin curves have been obtained. Complement was observed to be fixed in the reaction.Keywords
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