In Vitro Activities of Doripenem and Comparator Agents against 364 Anaerobic Clinical Isolates
Open Access
- 1 October 2005
- journal article
- research article
- Published by American Society for Microbiology in Antimicrobial Agents and Chemotherapy
- Vol. 49 (10) , 4413-4417
- https://doi.org/10.1128/aac.49.10.4413-4417.2005
Abstract
The in vitro activities of doripenem against 364 anaerobic isolates were measured and compared to those of ertapenem, imipenem, meropenem, ceftriaxone, and levofloxacin. All of the carbapenems were active against nearly all Bacteroides fragilis group isolates. Doripenem was either comparable to or slightly less active than imipenem and meropenem against most isolates but more active than the other penems against Clostridium difficile . Doripenem appears to have excellent activity against a broad range of anaerobes.Keywords
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