Viscosity and stability relations of the system ascorbic acid: water: polysorbate 20

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Abstract
The viscosity of dispersions of ascorbic acid in solutions of polysorbate 20 has been determined and found to be Newtonian at all concentrations studied. The course of the oxidation in polysorbate 20 appeared to be by the normal chain reaction, but the rate at which it occurred was modified by a number of factors. Incorporation within the micelle appeared to be responsible for an increase in oxidation rate, but the high viscosity of concentrated polysorbate 20 solutions, which would affect the diffusion of oxygen to the reaction site caused a much larger reduction in oxidation rate.

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