Nephropathy and Establishment of a Renal Reservoir of HIV Type 1 during Primary Infection
Top Cited Papers
Open Access
- 28 June 2001
- journal article
- case report
- Published by Massachusetts Medical Society in New England Journal of Medicine
- Vol. 344 (26) , 1979-1984
- https://doi.org/10.1056/nejm200106283442604
Abstract
Human immunodeficiency virus type 1 (HIV-1)–associated nephropathy is the chief cause of chronic renal disease in patients with HIV-1 infection and is now the third leading cause of end-stage renal disease in blacks 20 to 64 years of age.1,2 These patients typically have proteinuria followed by a reduction in the glomerular filtration rate that progresses to end-stage renal disease in a few weeks or months. HIV-1–associated nephropathy is characterized morphologically by focal segmental glomerulosclerosis, tubular microcysts, interstitial fibrosis, and inflammation.2-5Keywords
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