Ligand-induced Lysosomal Epidermal Growth Factor Receptor (EGFR) Degradation Is Preceded by Proteasome-dependent EGFR De-ubiquitination
Open Access
- 1 September 2003
- journal article
- Published by Elsevier in Journal of Biological Chemistry
- Vol. 278 (37) , 35781-35790
- https://doi.org/10.1074/jbc.m301326200
Abstract
No abstract availableKeywords
This publication has 46 references indexed in Scilit:
- Untangling the ErbB signalling networkNature Reviews Molecular Cell Biology, 2001
- The lore of the RINGs: substrate recognition and catalysis by ubiquitin ligasesTrends in Cell Biology, 2000
- Epidermal growth factor-related peptides and their receptors in human malignanciesPublished by Elsevier ,2000
- Ubiquitin Ligase Activity and Tyrosine Phosphorylation Underlie Suppression of Growth Factor Signaling by c-Cbl/Sli-1Molecular Cell, 1999
- Negative Regulation of Epidermal Growth Factor Signaling by Selective Proteolytic Mechanisms in the Endosome Mediated by Cathepsin BPublished by Elsevier ,1999
- c-Cbl/Sli-1 regulates endocytic sorting and ubiquitination of the epidermal growth factor receptorGenes & Development, 1998
- Endocytosis and intracellular sorting of receptor tyrosine kinasesFrontiers in Bioscience-Landmark, 1998
- Multivesicular endosomes containing internalized EGF-EGF receptor complexes mature and then fuse directly with lysosomes.The Journal of cell biology, 1996
- Kinase activity controls the sorting of the epidermal growth factor receptor within the multivesicular bodyCell, 1990
- Ligand-Induced Transformation by a Noninternalizing Epidermal Growth Factor ReceptorScience, 1990