Aspartate: Distinct Receptors on Aplysia Neurons
- 21 May 1976
- journal article
- research article
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 192 (4241) , 807-809
- https://doi.org/10.1126/science.4895
Abstract
Aplysia neurons have specific aspartate receptors that are distinct from those to glutamate. In some cells, aspartate selectively increases the membrane permeability to chloride, giving rise to a hyperpolarization, while on other cells it increases the permeability to sodium, causing a depolarization. There are also specific receptors for L-glutamate which mediate sodium, chloride, or potassium conductance increases, and another class of receptors activated by both glutamate and aspartate.Keywords
This publication has 20 references indexed in Scilit:
- Organisation of receptors for neurotransmitters on Aplysia neuronesNature, 1975
- Cooperative interaction of glutamate and aspartate with receptors in the neuromuscular excitatory membrane in walking limbs of the lobsterJournal of Neurobiology, 1975
- Determination of the relative potency of two excitant amino acidsNeuropharmacology, 1974
- Spinal interneurone excitation by conformationally restricted analogues of L-glutamic acidNature, 1974
- Determination of glutamate and glutamine in individual neurons of Aplysia californicaJournal of Neurochemistry, 1973
- THE FREE AMINO ACIDS IN PERIPHERAL NERVES AND IN ISOLATED INHIBITORY AND EXCITATORY NERVE FIBRES OF CANCER MAGISTER1Journal of Neurochemistry, 1973
- Structure-activity relationships of amino acid receptor sites on an identifiable cell body in the brain of the land snail Helix aspersaComparative Biochemistry and Physiology Part A: Physiology, 1972
- Bilateral Symmetry and Interneuronal Organization in the Buccal Ganglia of AplysiaScience, 1971
- A Contribution of an Electrogenic Na+ Pump to Membrane Potential in Aplysia NeuronsThe Journal of general physiology, 1968
- Action of glutamic acid and other naturally occurring amino-acids on snail central neuronsInternational Journal of Neuropharmacology, 1964