Primary adenocarcinomas of the larynx

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Abstract
Many of the clinicopathological features associated with primary glandular laryngeal tumors were seen in the 2 patients reported. Adenoid cystic carcinomas were seen in patients in the 6th or 7th decades. Most adenocarcinomas occurred in patients beyond the age of 60 yr. There appears to be a conspicuous male predominance in adenocarcinomas as opposed to a nearly equal sex involvement by adenoid cystic carcinomas. Adenocarcinomas are rarely subglottic. Supraglottic and transglottic involvement are about equal. Approximately 2/3 of adenoid cystic carcinomas are in subglottic structures. Both tumor types are lethal diseases. Widespread pulmonary and hepatic metastases are related to the outcome. Approximately 1/3 of patients with adenoid cystic carcinomas eventually show pulmonary metastases. The clinical course is more torpid with local recurrences and regional lymph node involvement. Primary radical surgery does not decrease the recurrence rate or prolong survival time. Wide local excision or conservative surgery wherever feasible is recommended as the treatment of choice for any glandular laryngeal tumor.

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