Incorporation of [14C]histidine into homocarnosine and carnosine of frog brain in vivo and in vitro
- 1 September 1969
- journal article
- Published by Portland Press Ltd. in Biochemical Journal
- Vol. 114 (3) , 585-588
- https://doi.org/10.1042/bj1140585
Abstract
1. Homocarnosine, carnosine and histidine were determined in brain from several species and the results compared with values in the literature. 2. [14C]Homocarnosine and [14C]carnosine were isolated from frog brain after intracerebral injection of [14C]histidine in vivo. 3. Whole frog brain, incubated in vitro with l-[14C]histidine, formed labelled homocarnosine and carnosine. 4. A frog brain homogenate or supernatant fraction catalysed the incorporation of l-[14C]histidine into homocarnosine and carnosine. 5. The results indicate that brain tissue can synthesize homocarnosine and carnosine.Keywords
This publication has 15 references indexed in Scilit:
- THE ISOLATION OF HOMOANSERINE FROM BOVINE BRAIN*†Journal of Neurochemistry, 1967
- A METHOD OF DETERMINATION OF HOMOCARNOSINE AND ITS DISTRIBUTION IN MAMMALIAN TISSUESJournal of Neurochemistry, 1967
- Isolation and identification of homocarnosine from bovine brainJournal of Neurochemistry, 1965
- Occurrence of homocarnosine (γ‐aminobutyrylhistidine) in the brain of Rana esculentaJournal of Neurochemistry, 1964
- Uptake of carnosine and homocarnosine by rat brain slicesArchives of Biochemistry and Biophysics, 1964
- The distribution of homocarnosine in mammalsArchives of Biochemistry and Biophysics, 1962
- Synthesis of homocarnosine in muscle in vivoBiochimica et Biophysica Acta, 1961
- ISOLATION OF GAMMA-AMINOBUTYRYLHISTIDINE (HOMOCARNOSINE) FROM BRAIN1961
- Carnosine-anserine synthetase of muscle I. Preparation and properties of a soluble enyzme from chick muscleBiochimica et Biophysica Acta, 1959
- [Beta-alanine and its compound in biological media].1953