Course of Depression During the Initiation of Interferon Beta-1a Treatment for Multiple Sclerosis

Abstract
INTERFERON beta-1a is approved by the Food and Drug Administration for treatment of patients with relapsing forms of multiple sclerosis (MS). Interferon beta-1a is well tolerated. Only 4% of the actively treated patients in an interferon beta-1a phase 3 clinical trial discontinued injections because of adverse effects.1 In clinical practice, 11% discontinue within 4 months of initiating treatment.2

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