Influence of Amino Acids upon Incidence of Tumors in Tu 50j Stock of D. melanogaster

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Abstract
Tu50j is a 2d chromosome recessive mutation, located near 90, and produces melanotic growths in the abdomen. Previous work had shown that a low caloric or poor nutrition diet inhibited tumor formation. In the present studies, using a rigorously controlled minimal diet to which different amino acids were added, it was found that excess amounts of tryptophan, lysine, and asparagine increased tumor incidence, but cystine, alanine, phenylalanine, and leucine decreased penetrance of tu50j. Tyrosine, glutamic acid, arginine, norleucine, histidine, methionine, and threonine have no apparent effect upon tu50J tumor formation.