MIGRATION OF LYMPHOCYTES AND THYMOCYTES IN THE RAT
Open Access
- 1 January 1968
- journal article
- Published by Rockefeller University Press in The Journal of Experimental Medicine
- Vol. 127 (1) , 155-168
- https://doi.org/10.1084/jem.127.1.155
Abstract
The cellular deficit in rats thymectomized at birth is primarily one of circulating small lymphocytes. The lymphocyte deficiency is similar to that induced in adult rats by chronic drainage from a thoracic duct fistula. In both cases, the animals show a reduction of small lymphocytes in peripheral blood, thoracic duct lymph, and in circumscribed areas of lymphoid tissue. The lympocyte deficiency in lymphoid tissue can be corrected by an intravenous injection of thoracic duct lymphocytes. The evidence suggests that the deficiency is corrected by small lymphocytes.Keywords
This publication has 26 references indexed in Scilit:
- The role of lymphocytes in antibody formation II. the influence of lymphocyte migration on the initiation of antibody formation in the isolated, perfused spleenProceedings of the Royal Society of London. B. Biological Sciences, 1967
- THE FUNCTIONS OF THE THYMUS SYSTEM AND THE BURSA SYSTEM IN THE CHICKENThe Journal of Experimental Medicine, 1966
- THYMUS-DEPENDENT AREAS IN THE LYMPHOID ORGANS OF NEONATALLY THYMECTOMIZED MICEThe Journal of Experimental Medicine, 1966
- ANTIBODY FORMATION INITIATED IN VITRO .3. ANTIBODY FORMATION AND ALLOTYPIC SPECIFICITY DIRECTED BY RIBONUCLEIC ACID FROM PERITONEAL EXUDATE CELLS1966
- Wasting Disease, Coombs-Positivity, and Amyloidosis in Rabbits Subjected to Central Lymphoid Tissue Extirpation and IrradiationInternational Archives of Allergy and Immunology, 1965
- Delineation of the Thymic and Bursal Lymphoid Systems in the ChickenNature, 1965
- The Thymus and the Development of Immunologic ResponsivenessScience, 1964
- CELL PROLIFERATION IN GERMINAL CENTERS OF THE RAT SPLEEN*Annals of the New York Academy of Sciences, 1964
- STUDIES OF THE PRIMARY AND THE SECONDARY IMMUNE RESPONSES OF LYMPH NODES DRAINING HOMOGRAFTS OF FRESH CANCELLOUS BONE (WITH PARTICULAR REFERENCE TO MECHANISMS OF LYMPH NODE REACTIVITY)Annals of the New York Academy of Sciences, 1962
- The Effect of Thymectomy on the Lymphoid Tissues of the MouseBritish Journal of Haematology, 1960