Analysis of Candida albicans phenotypes from different geographical and anatomical sources

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Abstract
Strain phenotypes of 330 C. albicans isolates from 5 areas in the USA were determined on the basis of 9 biochemical tests. Statistical analysis of the distribution of phenotypes revealed no significant differences among types from different anatomical sources. There were some differences among the phenotypes of strains from the different geographical areas; there were substantial differences in biochemical phenotypes associated with strains susceptible and resistant to 5-fluorocytosine and between strains of serotypes A and B. Geographical differences in phenotypes of C. albicans were also noted between the 330 USA isolates and 247 isolates from Britain [UK]. Cluster analysis of the USA strains alone and of all of the USA and UK strains showed that C. albicans phenotypes can be grouped into < 20 clusters with common biochemical properties.