Nucleotide Sequence of the Putative Human Tyrosinase Pseudogene.
- 1 January 1991
- journal article
- Published by Tohoku University Medical Press in The Tohoku Journal of Experimental Medicine
- Vol. 163 (4) , 295-297
- https://doi.org/10.1620/tjem.163.295
Abstract
TAKEDA, A., MATSUNAGA, J., TOMITA, Y., TAGAMI, H. and SHIBAHARA, S. Nucleotide Sequence of the Putative Human Tyrosinase Pseudogene. Tohoku J. Exp. Med., 1991, 163 (4), 295-297- We have cloned and sequenced the putative human tyrosinase pseudogene, which shares more than 98% nucleotide homology with exon 4 and exon 5 of the human tyrosinase gene including their flanking introns. Because of such a high homology, both the tyrosinase gene and its pseudogene could be amplified from genomic DNA by polymerise chain reaction. The nucleotide sequences presented thus enable us to discriminate the tyrosinase gene from its related sequences and are invaluable for a gene diagnosis of oculocutaneous albinism.Keywords
This publication has 0 references indexed in Scilit: