Acute Necrotizing Encephalitis

1 February 1962

journal article
research article
Published by American Medical Association (AMA) in Archives of Neurology

Vol. 6 (2) , 96-113
https://doi.org/10.1001/archneur.1962.00450200010002

Abstract

Introduction The name "acute necrotizing encephalitis" (ANE), as coined by van Bogaert, Radermecker, and Devos¹in 1955, is used to designate a form of meningoencephalitis characterized by softening of the temporal lobes and related rhinencephalic structures, and microscopically by an extensive necrosis of these areas. During the past 2 decades, 59 cases of similar clinical and anatomical findings in patients over 1 year of age with a duration of illness less than 4 weeks have appeared in the literature.^1-25Patients under 1 year of age were omitted because the necrosis tends to be more generalized. The duration of illness was limited to 4 weeks to emphasize the acute diagnostic problem. In 46 of these, Type A intranuclear inclusions were found in nerve or neuroglial cells^1-16; of 20 cases in which viral isolation studies were made on brain tissue,^*13 were positive for herpes simplex.^{2,3,11,12,15-20}The remaining

Keywords

This publication has 0 references indexed in Scilit: