Quantitative Aspects of the Nicotinic Acid–Tryptophan Interrelationship in Chick

Publisher Website
Google Scholar
Abstract
In chicks on a 20% protein diet, 0.15% of L-tryptophan is adequate. Moreover, L-tryptophan can apparently completely replace dietary nicotinic acid, Since 0.15% L-tryptophan with 2.5 mg nicotinic acid per 100 g diet was as effective as 0.20% L-tryptophan, efficiency of replacement of nicotinic acid by tryptophan was about 1 : 20. The nicotinic acid requirement appeared to be conditioned by balance of certain amino acids in the diet. Small amounts of histidine, threonine and leucine produced a high incidence of perosis which could be prevented by about 10 mg of nicotinic acid per 100 g of diet. Addition of corn (maize) to the diet produced a stress condition thought due to its amino acid content, which responded to the addition of 10 mg of nicotinic acid per 100 g diet.