Chromatographic analysis of cholesterol esters in fetal brain serum and spinal fluid

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Abstract
A simple semiquantitatlve method is presented for determination of native cholesterol esters in brain, spinal fluid, and serum by silica gel paper chromatography. In fetal brain there are the same fractions of cholesterol esters as in serum of adults, but in a reversed ratio. Saturated fatty acids show the highest and dienoic fatty acids the lowest concentration. In postmortem fetal cisternal fluid the cholesterol ester pattern is very similar to fetal serum, in which the fraction of monoenoic fatty acid cholesterideg predominates.