COORDINATION OF GASTROINTESTINAL HORMONES AND AUTONOMIC NERVES

  • 1 January 1978
    • journal article
    • research article
    • Vol. 69  (1) , 21-50
Abstract
Investigations were conducted on the relationship between gastrointestinal hormones and the autonomic nervous system. A close association between gastrointestinal hormones and the autonomic nervous system was shown from the functional and morphological points of view. [Dogs and rats were studied.] The nervism proposed by Pavlov, where the regulation of various organs in the body was thought to be accomplished wholly by the nervous system, was based on the findings on the physiology of the digestive glands. In the meantime, the discovery of secretin from the duodenal mucosa led Bayliss and Starling to propose a chemical coordination or a humoral regulatory mechanism in addition to the nervous system for the regulation of the various organ in the body. It is surprising that the principle of 2 major regulatory mechanisms in the body was thus developed originally on the basic studies of the exocrine and endocrine function of the digestive system.