Regular Involvement of Clarke's Nucleus in Sporadic Amyotrophic Lateral Sclerosis
- 1 March 1982
- journal article
- research article
- Published by American Medical Association (AMA) in Archives of Neurology
- Vol. 39 (3) , 155-156
- https://doi.org/10.1001/archneur.1982.00510150025006
Abstract
• Morphometric study of Clarke's nucleus in 12 cases of sporadic amyotrophic lateral sclerosis and 12 normal control subjects showed an average 36% reduction in the neuronal population in the disease group, with involvement in each case. Histopathologic findings of cell degeneration were definite but less noticeable than in the ventral horns. The process seems likely to be similar to that affecting motor neurons but is less advanced at the time of death.This publication has 5 references indexed in Scilit:
- What Does Imaging Reveal About the Pathology of Amyotrophic Lateral Sclerosis?Current Neurology and Neuroscience Reports, 2015
- Pathological involvement of primary sensory neurons in Werdnig-Hoffmann diseaseActa Neuropathologica, 1978
- The central nervous system in motor neurone diseaseJournal of Neurology, Neurosurgery & Psychiatry, 1970
- Proximal axonal enlargement in motor neuron diseaseNeurology, 1968
- Familial Amyotrophic Lateral SclerosisArchives of Neurology, 1967