The Effect of Diftalone on Collagen and Glycosaminoglycans Metabolism
- 1 January 1976
- journal article
- research article
- Published by S. Karger AG in Pharmacology
- Vol. 14 (5) , 414-421
- https://doi.org/10.1159/000136623
Abstract
Diftalone showed a distinct inhibition effect on collagen formation in sponge granuloma of rats and in chick embryo articular cartilage. The inhibitory effect was expressed in corneal and articular cartilage glycosaminoglycans (GAG) sulfation and GAG formation in granulation tissue. According to previous results diftalone showed a similar inhibition of collagen and GAG biosynthesis as other effective antirheumatic drugs.This publication has 2 references indexed in Scilit:
- Micro separation and determination of mammalian acidic glycosaminoglycans (mucopolysaccharides)Analytical Biochemistry, 1967
- The determination of glucosamine and galactosamineBiochemical Journal, 1955