Bone tumours induced in rats with radioactive cerium
Open Access
- 30 April 1980
- journal article
- research article
- Published by Springer Nature in British Journal of Cancer
- Vol. 41 (5) , 809-815
- https://doi.org/10.1038/bjc.1980.145
Abstract
A technique is described for the induction of metastasizing bone tumours in rats by local inoculation of 144cerium. Bone sarcomas develop in 90% of the animals and 74% of these had lung metastases. The tumours can be easily cultured and maintained by serial transplantations. Preliminary data of clinical, histological and kinetic characteristics of these bone tumours are given.Keywords
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