AKAP-Mediated Targeting of Protein Kinase A Regulates Contractility in Cardiac Myocytes
- 16 February 2001
- journal article
- other
- Published by Wolters Kluwer Health in Circulation Research
- Vol. 88 (3) , 291-297
- https://doi.org/10.1161/01.res.88.3.291
Abstract
—Compartmentalization of cAMP-dependent protein kinase A (PKA) by A-kinase anchoring proteins (AKAPs) targets PKA to distinct subcellular locations in many cell types. However, the question...Keywords
This publication has 34 references indexed in Scilit:
- Selectivity and Regulation of A-kinase Anchoring Proteins in the HeartJournal of Biological Chemistry, 2000
- PKA Phosphorylation Dissociates FKBP12.6 from the Calcium Release Channel (Ryanodine Receptor): Defective Regulation in Failing HeartsPublished by Elsevier ,2000
- Impaired cardiomyocyte relaxation and diastolic function in transgenic mice expressing slow skeletal troponin I in the heartThe Journal of Physiology, 1999
- A-kinase Anchoring Protein 100 (AKAP100) is Localized in Multiple Subcellular Compartments in the Adult Rat HeartThe Journal of cell biology, 1998
- Effects of endothelin-1 on [Ca2+]i-shorteningtrajectory and Ca2+ sensitivity in rabbit single ventricular cardiomyocytes loaded with Indo-1/AM: Comparison with the effects of phenylephrine and angiotensin IIJournal of Cardiac Failure, 1996
- Regulation of phospholamban and troponin-I phosphorylation in the intact rat cardiomyocytes by adrenergic and cholinergic stimuli: roles of cyclic nucleotides, calcium, protein kinases and phosphatases and depolarizationMolecular and Cellular Biochemistry, 1995
- Regulation of cAMP-dependent protein kinase: Enzyme activation without dissociationBiochemistry, 1995
- Cloning and Characterization of A-kinase Anchor Protein 100 (AKAP100)Journal of Biological Chemistry, 1995
- Phosphorylation of troponin I and phospholamban during catecholamine stimulation of rabbit heartNature, 1982
- Phosphorylation of troponin I and the inotropic effect of adrenaline in the perfused rabbit heartNature, 1976