Multiple Forms of Serum and Liver Esterases in the Normal State and in Cirrhosis of the Liver

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Abstract
Several esterases in human serum and hepatic tissue were studied by electrophoresis in agar gel. Four esterase fractions were observed in serum and six or seven such fractions in hepatic tissue. It was found that, in liver cirrhosis, a marked reduction of aromatic esterases and of cholinesterase occurs in the liver and in the serum. This reduction appears, however, to be much less marked at the tissue level than in the serum. The fall of aromatic esterases seems to be even more typical than that of cholin-esterase. In fact, in the serum some aromatic esterase fractions could completely disappear.

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