Cyclohexenonic Long-Chain Fatty Alcohols as Neuronal Growth Stimulators
Open Access
- 22 December 2000
- Vol. 5 (12) , 1439-1460
- https://doi.org/10.3390/51201439
Abstract
Neurotrophic factors play an important role in the development and maintenance of neurons, thus providing a suitable therapeutic approach for the treatment of neurodegenerative diseases. However, their clinical use has revealed problematic because of a number of technical and biological disadvantages. Among the different strategies proposed to overcome such difficulties, the search for non-peptide substances with neurotrophic potential is giving promising results. Here we will expose major findings in this field, drawing special attention to cyclohexenonic long-chain fatty alcohols, a novel family of compounds that promote neuronal survival and neurite outgrowth.Keywords
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