PLASMA ANTI-THROMBIN-III ACTIVITY IN NORMAL-PREGNANCY

  • 1 January 1980
    • journal article
    • research article
    • Vol. 56  (5) , 601-603
Abstract
The incidence of thromboembolic phenomena increases in pregnancy. Antithrombin III has been implicated as a possible etiologic factor for the increase of thromboembolic phenomena in women receiving exogenous estrogens. In a study of normal obstetric, postpartum and oral contraceptive [norethindrone, mestranol] patients, no significant change in antithrombin III activity could be detected in a plasma-based assay within and among these groups. A decrease in antithrombin III activity may not be a cause of increased thromboembolic phenomena during normal pregnancy and oral contraceptive use.

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