COMPARATIVE STUDIES ON IMMUNODIAGNOSIS OF FILARIASIS

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  • 1 January 1976
    • journal article
    • research article
    • Vol. 27  (3) , 377-384
Abstract
Four serological methods were evaluated for the immunodiagnosis of filarial infections in European patients returning from endemic areas. The highest sensitivity was found by immunoelectrophoresis (73%), followed by the indirect fluorescence antibody test (60%) and the indirect hemagglutination (57%). The reliability of 2-dimensional gel diffusion was rather low (41%). Using immunofluorescence and hemagglutination procedures simultaneously, 83% of all pathologic filarial infections were detectable. By adding an immunoelectrophoretic analysis to those sera which gave doubtful results, a final sensitivity of 88% was attained.

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