Abstract
Previous expts. suggested that indoleacetic acid in corn might be responsible for growth inhibition of rats maintained on diets low in nicotinic acid and tryptophan. The addition of 25 to 200 mg./day of indoleacetic acid for 6 to 8 days appeared to have no significant effect upon the utilization of tryptophan and nicotinic acid by man, as evidenced by the urinary excretion of nicotinic acid, N[image]-methylnicotinamide, tryptophan, and related metabolites, by subjects maintained on a controlled diet, low in protein and nicotinic acid.