Survival and cause of death after mitral valve replacement in patients aged 80 years and over Collective results from the UK heart valve registry

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Abstract
OBJECTIVE: Over the last decade there has been an increasing number ofpatients aged 80 years and over undergoing heart valve replacement.However, literature on the outcome of mitral valve replacement (MVR) inthis age group is still limited. METHODS: We conducted the present study byanalysing data extracted from the UK Heart Valve Registry. From January1986 to December 1994, 86 patients underwent isolated MVR and 10 underwentcombined MVR with aortic valve replacement (AVR) and were reported to theRegistry. RESULTS: The 30 day mortality was 10.4% (9/86) in the MVR groupand 10% (1/10) in the MVR and AVR group. The actuarial survival was 79.8,64.1 and 40.7% at 1, 3 and 5 years, respectively, in the MVR group. Of the10 early (30 day) deaths, 8 were due to cardiac reasons and 19 of the 28late deaths were due to non- cardiac reasons. A total of 55 (57.2%)patients received a bioprosthetic valve implant and 41 (42.8%) patientsreceived a mechanical valve implant. There was no difference in survivalbetween the two groups. CONCLUSIONS: The above results suggest that MVR inoctogenarians produces a satisfactory early postoperative outcome andmoderate medium-term benefit. There is no difference in survival betweenpatients receiving bioprosthetic and patients receiving mechanical valveimplants.

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