Relation between the Stromal Volume and Liver Metastasis in Ductal Cell Carcinoma of the Pancreas.

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Abstract
In 23 patients with ductal cell carcinoma of the pancreas, the volume density of the stromal area was estimated by morphometry on photomicrographs of cancer tissue taken at surgery. The patients were divided into three groups: those with metachronous liver metastasis (Group A, n = 8), with simultaneous liver metastasis (Group B, n = 4) and those without liver metastasis (Group C, n = 11). The analysis illustrated a significantly lower fraction of stromal element in Groups A and B as compared to Group C at a statistical level of 0.01 (Ryan test). The scirrhous pancreatic carcinoma tended to resist liver metastasis after various therapeutic modalities including pancreatic resection.

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