SURGICAL-TREATMENT OF DERMATOFIBROSARCOMA PROTUBERANS

  • 1 May 1986
    • journal article
    • research article
    • Vol. 162  (5) , 449-452
Abstract
The clinical course and histopathologic factors of 50 consecutive patients treated for dermatofibrosarcoma protuberans were reviewed. Forty-eight patients were observed until the present time or death. No patient had distant metastases develop, although 16 patients had 18 recurrences of the dermatofibrosarcoma protuberans at the site of initial therapy. There was no correlation between the diameter of the primary lesion and the incidence of recurrence. There was no correlation between histologic pattern of invasion and recurrence. However, a trend toward decreasing recurrence was noted with increasing minimal margins of resections (41 per cent < 2 centimeters versus 24 per cent .gtoreq. 2 centimeters). The lowest incidence of recurrence (20 per cent) was noted with minimal margins of resection .gtoreq. 3 centimeters. Five year recurrence free survival rates increased with increasing margins of resection-59 per cent < 1 centimeter; 66 per cent .gtoreq. 1 centimeter; 70 per cent .gtoreq. 2 centimeters, and 80 per cent .gtoreq. 3 centimeters. No patient had distant metastases and no change in histologic pattern was noted with progressive local recurrence.

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