Phorbol myristate acetate (PMA) augments chemoattractant-induced diglyceride generation in human neutrophils but inhibits phosphoinositide hydrolysis. Implications for the mechanism of PMA priming of the respiratory burst.
Open Access
- 1 September 1988
- journal article
- research article
- Published by Elsevier in Journal of Biological Chemistry
- Vol. 263 (26) , 13191-13198
- https://doi.org/10.1016/s0021-9258(18)37690-7
Abstract
No abstract availableThis publication has 67 references indexed in Scilit:
- The common structure and activities of four subspecies of rat brain protein kinase C familyFEBS Letters, 1987
- The diacylglycerol kinase inhibitor R59022 potentiates superoxide production but not secretion induced by fMet-Leu-Phe: Effects of leupeptin and the protein kinase C inhibitor H-7Biochemical and Biophysical Research Communications, 1987
- Comparative effects of polymyxin B, phorbol ester and bryostatin on protein phosphorylation, protein kinase C translocation, phospholipid metabolism and differentiation of HL60 cellsBiochemical and Biophysical Research Communications, 1987
- The diacylglycerol kinase inhibitor, R59022, enhances the superoxide generation from human neutrophils induced by stimulation of fMet-Leu-Phe, IgG and C3b receptorsBiochemical and Biophysical Research Communications, 1987
- Double stimulation with FMLP and Con A restores the activation of the respiratory burst but not of the phosphoinositide turnover in Ca2+-depleted human neutrophils. A further example of dissociation between stimulation of the NADPH oxidase and phosphoinositide turnoverBiochemical and Biophysical Research Communications, 1986
- Cloning and expression of multiple protein kinase C cDNAsCell, 1986
- Differential mechanisms of translocation of protein kinase C to plasma membranes in activated human neutrophilsBiochemical and Biophysical Research Communications, 1986
- Phorbol 12, myristate 13, acetate potentiates the respiratory burst while inhibits phosphoinositide hydrolysis and calcium mobilization by formyl-methionyl-leucyl-phenylalanine in human neutrophilsBiochemical and Biophysical Research Communications, 1986
- Polymyxin B inhibits phorbol 12‐myristate 13‐acetate, but not chemotactic factor, induced effects in rabbit neutrophilsFEBS Letters, 1985
- Diacylglycerol, 1-oleoyl-2-acetyl-glycerol, stimulates superoxide-generation from human neutrophilsBiochemical and Biophysical Research Communications, 1984