VARIOUS TYPES OF EMBRYO--ENDOMETRIAL CONTACTS DURING DELAY OF IMPLANTATION IN THE MOUSE

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Abstract
Summary. A gradual closure of the uterine lumen occurs during progesterone treatment of mice spayed in early pregnancy. This causes an appearance of various imprints by the endometrium on the blastocyst. Imprints bounded by a polygonal circumference are caused by the slightly protruding intercellular borders of the endometrium. Shallow imprints appearing later are produced by bulging epithelial cells. Deep, rounded imprints are caused by fungus-like protrusions of the luminal epithelium. Generally, imprints are more frequent on the blastocyst surface than on the endometrial surface, suggesting that the trophoblast cells are more malleable than uterine epithelial cells in delayed implantation. The good correlation between structures in scanning and transmission electron micrographs indicates that the preparation techniques used are satisfactory.
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