RHEOLOGICAL EVALUATION OF HEMOGLOBIN-S AND HEMOGLOBIN-C HEMOGLOBINOPATHIES

  • 1 January 1977
    • journal article
    • research article
    • Vol. 89  (3) , 488-497
Abstract
The concept of optimum hematocrit was used to compare the rheology of bloods from patients with various Hb S and Hb C hemomoglobinopathies. The technique involved the utilization of cone and plate viscometric data to predict average flow rates under representative physiological-fluid mechanical conditions. The shape of the curve relating optimum hematocrit to O2 tension, rather than the absolute magnitude of the optimum hematocrit at fixed O2 tension, is shown to give an indication of clinical severity of the disease.

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