Activity of serum cytidine deaminase during pregnancy
- 1 April 1982
- journal article
- research article
- Published by Wiley in BJOG: An International Journal of Obstetrics and Gynaecology
- Vol. 89 (4) , 314-317
- https://doi.org/10.1111/j.1471-0528.1982.tb04703.x
Abstract
Summary. A simple and reliable method for the estimation of cytidine deaminase (cytidine aminohydrolase; EC 3.5.4.5) activity in pregnancy serum is described. This enzyme does not require magnesium for activation and is also more stable than deoxycytidylate deaminase (dCMP deaminase, dCMP aminohydrolase; EC 3.5.4.12). There was excellent correlation between the two enzymes (r= 0.92). Both enzymes showed increased activity in abnormal pregnancy. Both enzyme activities were found to be similar in 1305 maternal serum samples and therefore due to the simplicity of cytidine deaminase estimation it is recommended for the screening of large numbers of antenatal sera for abnormal pregnancies.This publication has 3 references indexed in Scilit:
- PLASMA URATE AND SERUM DEOXYCYTIDYLATE DEAMINASE MEASUREMENTS FOR THE EARLY DIAGNOSIS OF PRE‐ECLAMPSIABJOG: An International Journal of Obstetrics and Gynaecology, 1977
- A rapid method for the determination of deoxycytidylate deaminase activity in pregnancy serumClinica Chimica Acta; International Journal of Clinical Chemistry, 1975
- Deoxycytidylate deaminase in pregnancy.BMJ, 1975