Mutations of the ELA2 gene found in patients with severe congenital neutropenia induce the unfolded protein response and cellular apoptosis
Open Access
- 15 December 2007
- journal article
- Published by American Society of Hematology in Blood
- Vol. 110 (13) , 4179-4187
- https://doi.org/10.1182/blood-2006-11-057299
Abstract
Severe congenital neutropenia (SCN) is an inborn disorder of granulopoiesis. Mutations of the ELA2 gene encoding neutrophil elastase (NE) are responsible for moKeywords
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