The Use of a 10-Day Period for the Assay of Vitamin B by Rat Growth Technic
- 1 December 1936
- journal article
- research article
- Published by Elsevier in Journal of Nutrition
- Vol. 12 (6) , 583-596
- https://doi.org/10.1093/jn/12.6.583
Abstract
A short period technic for vitamin B assays has been developed through a study of the factors producing variability in results. The amount of growth of the rat during 10 days was found to be a valid criterion of the quantity of vitamin B in the dose material if the following precautions had been observed. The quantity of vitamin B causing 1 gm. of gain, when the rate of gain has been limited to 1 to 2 gm. per day, is suggested as a unit since it is comparable to the minimum curative dose defined by Ammerman and Waterman.Keywords
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