The Effect of Haemodialysis on Tubular Secretion of Creatinine in Residual Nephrons
- 1 January 1990
- journal article
- Published by Oxford University Press (OUP) in Nephrology Dialysis Transplantation
- Vol. 5 (7) , 549-550
- https://doi.org/10.1093/ndt/5.7.549
Abstract
In a group of 16 patients on regular haemodialysis treatment, inulin and creatinine clearance was examined before and 12 h after haemodialysis. Inulin clearance (CIn) decreased significantly (P less than 0.001) whereas creatinine clearance (CCr) did not change after haemodialysis. The CCr/CIn ratio increased significantly (P less than 0.05) as did calculated tubular secretion of creatinine (TCr) (P less than 0.01) and TCr/CIn 100 (P less than 0.001). The results suggest that uraemic sera contain dialysable substance(s) depressing tubular secretion of creatinine.Keywords
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