Chimeric Mice with Donor-Type Liver Cells
- 15 April 1966
- journal article
- research article
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 152 (3720) , 349-352
- https://doi.org/10.1126/science.152.3720.349
Abstract
C3H mice, made chimeric by lethal x-irradiation followed by injection of (C3H x T6)F1 spleen cells, were later stimulated by CCl4 to produce a vigorous burst of hepatic parenchymal cell mitoses. Cytogenetic studies of the regenerating livers of 11 chimeras identified 89 percent of the cells as donor type by the presence of the distinctive T6 marker.This publication has 16 references indexed in Scilit:
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