1H- and2H-n.m.r. Studies of Water in γ-irradiated Phosphatidylcholine Multilamellar Liposomes

1 January 1985

journal article
research article
Published by Taylor & Francis in International Journal of Radiation Biology

Vol. 48 (1) , 117-125
https://doi.org/10.1080/09553008514551121

Abstract

¹H- and ²H-n.m.r. studies of γ-irradiation-induced variations in the dynamic structure and proportional amounts of free, trapped and bound water species in multilamellar liposomes are reported and discussed. Bound water is shown to increase with dose and to be present in two different structural states. A dose-dependent decrease in the ¹H-n.m.r. relaxation times of bound water following γ-irradiation is reported. Variations are suggested as being due to large scale changes at the bilayer surface.

Keywords

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